Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
Carl C. Peck (auth.), Avraham Yacobi Ph.D., Jerome P. Skelly Ph.D., Vinod P. Shah Ph.D., Leslie Z. Benet Ph.D., Pharm.D.(Hon.) (eds.)
Introduction: The Case for Preclinical Pharmacodynamics (G. Levy). Preclinical Pharmacokinetic and Pharmacodynamic Studies: Pharmacokinetics and Drug Metabolism in Animal Studies (G.G. Fitzgerald). Methodology for Preclinical Pharmacodynamic Studies: Preclinical Pharmacodynamics of Central Nervous System Active Agents (M. Danhof et al.). Preclinical and Clinical Pharmacokinetics: The Role of Pharmacokinetics in the Drug Development Process (L.Z. Benet). Clinical Pharmacodynamics: The Value of PlasmaWayfarin Measurement (R.A. O'Reilly). Application of Pharmacodynamics and Pharmacokinetics in the Drug Development Process: ConcentrationControlled Trials (L. Sanathanan, C.C. Peck). Summary Report: Opportunities for Integration of Pharmacokinetics, Pharmcodynamics, and Toxicokinetics in Rational Drug Development. 19 additional articles. Index.
Kategoriler:
Yıl:
1993
Baskı:
1
Yayımcı:
Springer US
Dil:
english
Sayfalar:
270
ISBN 10:
1475715226
ISBN 13:
9781475715224
Dosya:
PDF, 16.14 MB
IPFS:
,
english, 1993
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